Cost · Compounded GLP-1

Compounded vs. Branded
GLP-1 Savings Calculator

See your exact monthly and annual savings switching from branded Wegovy or Zepbound to compounded semaglutide or tirzepatide.

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Results are estimates based on published research. Individual results vary. Not medical advice.
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How much cheaper is compounded semaglutide than Wegovy?

Compounded semaglutide costs 75 to 89% less than branded Wegovy in 2026. Wegovy list price is approximately $1,349 per month; compounded semaglutide through licensed telehealth providers starts at $146 per month on a 6-month plan. The annual saving for a patient switching from uninsured Wegovy to compounded semaglutide at $199 per month is approximately $13,800.

The active ingredient in compounded semaglutide is identical to Wegovy and Ozempic — semaglutide — prepared by US-licensed compounding pharmacies under FDA oversight. The key differences are that compounded versions are not FDA-approved as finished drug products and may contain additional ingredients such as vitamin B12.

Is compounded semaglutide safe? Compounded semaglutide is legal in 2026 when dispensed by licensed 503A or 503B pharmacies through a valid physician prescription. Reputable telehealth providers work exclusively with FDA-registered facilities.

Compounded vs branded — what's the difference?

The active molecule is identical. The main differences are: compounded versions are not FDA-approved as finished products; auto-injector devices differ; some compounded formulations include vitamin B12 not present in Wegovy; and branded medications have longer post-market safety records. For most patients, the cost savings justify switching — especially when the alternative is stopping treatment entirely.

Frequently asked questions
Compounded semaglutide costs 75 to 89% less than branded Wegovy. Wegovy list price is approximately $1,349 per month; compounded semaglutide starts at $146 per month. The annual saving switching from uninsured Wegovy to compounded semaglutide at $199 per month is approximately $13,800.
Yes, compounded tirzepatide remains available through licensed telehealth providers in 2026. Multiple court decisions have maintained the legality of compounding for individual patients through licensed 503A pharmacies. Compounded tirzepatide is available from $258 per month, compared to $1,059 per month for branded Zepbound.
Switching is worth considering if cost is a barrier to staying on treatment, since treatment discontinuation has the highest health cost of all. The active ingredient is identical. If you are paying full list price for Wegovy, switching to compounded semaglutide at $146 to $275 per month typically makes financial sense.
Yes. Both HSA and FSA funds can be used to pay for GLP-1 medications, including compounded versions, when prescribed by a licensed physician. Since these require a prescription, they qualify as eligible medical expenses. Using HSA or FSA effectively reduces cost by 22 to 37% depending on your tax bracket.
Save up to $1,200/mo on GLP-1 Compounded from $146/mo
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Compounded from $146/mo
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