Compounded vs. Branded
GLP-1 Savings Calculator
See your exact monthly and annual savings switching from branded Wegovy or Zepbound to compounded semaglutide or tirzepatide.
See your exact monthly and annual savings switching from branded Wegovy or Zepbound to compounded semaglutide or tirzepatide.
Compounded semaglutide costs 75 to 89% less than branded Wegovy in 2026. Wegovy list price is approximately $1,349 per month; compounded semaglutide through licensed telehealth providers starts at $146 per month on a 6-month plan. The annual saving for a patient switching from uninsured Wegovy to compounded semaglutide at $199 per month is approximately $13,800.
The active ingredient in compounded semaglutide is identical to Wegovy and Ozempic — semaglutide — prepared by US-licensed compounding pharmacies under FDA oversight. The key differences are that compounded versions are not FDA-approved as finished drug products and may contain additional ingredients such as vitamin B12.
Is compounded semaglutide safe? Compounded semaglutide is legal in 2026 when dispensed by licensed 503A or 503B pharmacies through a valid physician prescription. Reputable telehealth providers work exclusively with FDA-registered facilities.
The active molecule is identical. The main differences are: compounded versions are not FDA-approved as finished products; auto-injector devices differ; some compounded formulations include vitamin B12 not present in Wegovy; and branded medications have longer post-market safety records. For most patients, the cost savings justify switching — especially when the alternative is stopping treatment entirely.